Santa Clara vs San Francisco Picks and Predictions for Saturday, February 21, 2026

By: Cameron Ross Published 02/21/2026, 04:15 AM ET

Santa Clara vs San Francisco Information

The Santa Clara Broncos will be on the road Saturday night with a 10:00 PM matchup in San Francisco, CA against the San Francisco Dons. Santa Clara has 22 wins and six losses this season, following an 8-point home loss to Gonzaga in their last outing to end a lengthy winning streak. The San Francisco Dons stay home Saturday with 15 wins and 14 losses this season, having lost four of the last five after a 21-point loss in their last game. Stay in the action with our College Basketball Picks.

Santa Clara Preview

The Santa Clara offense is rolling this season, averaging 83.7 points on 47% shooting from the floor this season. Defensively, Santa Clara has been just a stout holding opponents to 71.9 points per game this season, but gave up 94 points in their loss to Gonzaga. Christian Hammond leads the Santa Clara offense this season, with 16.4 points per game. Elijah Mahi is second on the team, with 13.8 points per game this season. Allen Graves averages 11.4 points to go along with the team’s leading 6.9 rebounds. Jake Ensminger is averaging 6.4 points to go along with the team-leading 3 assists per game.

San Francisco Preview

Offensively, San Francisco scores the ball well enough this season, averaging 74.5 points on 43% shooting from the floor. Defensively, San Francisco is allowing 73 points per game this season, but has given up an average of 83.25 points per game over their last four losses. Ryan Beasley leads the San Francisco offense this season with 13.4 points and 3.9 assists. David Fuchs averages 11.7 points to go along with the team-leading 7.3 rebounds. Tyrone Riley IV is third on the roster with 11.6 points per game this season.

Santa Clara vs San Francisco Prediction

Santa Clara is a far better team in this matchup, and it will show from the opening minutes on Saturday. Look for the Broncos to dominate this game on both sides of the ball as they overwhelm a struggling San Francisco team. Take the Broncos and use their edge on both ends of the floor do the job as they continue to roll. Santa Clara will get the win and cover at home Saturday night to pick up their 23rd victory of the season. Final Score Prediction, Santa Clara Broncos win and cover 83-70.

Subscribe Now

I authorize Picks And Parlays to send me promotional emails

I understand that I can unsubscribe at any time. I have read and accepted the Terms & Conditions and Privacy Policy. I consent that Picks And Parlays may use third-party services to process my data.

Terms & Conditions

Betting on College Basketball?

Join Picks and Parlays premium for free and get a free $30 coupon with code FREE30
Get started and wager on college hoops today with our favorite online sportsbooks
Claim a CBB betting bonus offer with the best sportsbook promos