SE Louisiana at Ole Miss Picks and Predictions for Monday, November 3, 2025 

By: David Anicetti Published 11/02/2025, 10:27 PM ET

The college basketball season opens in Oxford on Monday night as Ole Miss hosts Southeastern Louisiana at The Sandy and John Black Pavilion. Chris Beard’s Rebels look to build on last season’s NCAA Tournament return, while David Kiefer’s Lions have a retooled roster looking to test itself early against SEC competition. Tip-off is scheduled for 8:00 p.m. ET on SECN+. Make the winning jump shot with our college basketball picks

Game Information for SE Louisiana vs Ole Miss

Location: The Sandy and John Black Pavilion, Oxford, MS

Time: 8:00 p.m. ET

Coverage: SECN+

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Southeastern Louisiana Lions Preview

The Lions return five players from last season’s 18–14 team, led by forward Jeremy Elyzee, the reigning Southland Conference Freshman of the Year. Head coach David Kiefer has built around Elyzee’s versatility and added a strong transfer class to boost depth. Fifth-year players Ethan Pickett and Isaiah Gaines join guards Seth Jones from Pacific and Ubong-Abasi Etim from Bowling Green, creating a roster with more size and experience than in recent years.

Athleticism and defense are points of emphasis this season, and Kiefer has praised his team’s play through preseason workouts. Still, facing an SEC opponent on opening night is a significant challenge for a unit with 10 newcomers. The Lions’ non-conference schedule is among the toughest in the Southland, and oddsmakers reflect that with a big spread for this matchup in Oxford.

Ole Miss Rebels Preview

Chris Beard’s team begins the season positioned as a projected NCAA Tournament team and top-half SEC contender. Ole Miss returns senior forward Malik Dia, while adding several high-impact transfers, including guard Koren Johnson from Louisville and forward AJ Storr from Kansas. The Rebels finished 24–12 a year ago behind balanced scoring and a defense that improved as the season progressed.

Beard’s emphasis on rebounding and half-court defense should stand out against smaller non-conference opponents. The roster features more length and a deeper bench, giving Ole Miss a clear advantage inside and in transition. The Rebels open as heavy favorites, with the total set in the low 140s, with the game influenced by the defense.

SE Louisiana at Ole Miss Prediction

Ole Miss has the advantage in experience, talent, and depth. The Rebels will be up by double digits by halftime, while Southeastern Louisiana’s transition defense will be tested against the talented Ole Miss players. Expect Ole Miss to dictate tempo, win the battle on the boards, and start the season with a comfortable home victory. Final Score Prediction: Ole Miss Rebels win and cover ATS, 82–55.

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Best Picks

  • Ole Miss Rebels -23.5
  • Under 141.5
  • First Half Ole Miss -12
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