South Carolina Gamecocks vs Clemson Tigers Picks and Predictions for Tuesday, December 16, 2025

By: David Anicetti Published 12/16/2025, 12:05 AM ET

The South Carolina Gamecocks visit the Clemson Tigers on Tuesday night at Littlejohn Coliseum. South Carolina is 7–3 overall and opens its true road play after a 71–55 win over The Citadel in its most recent game. Clemson is 8–3 overall and a perfect 6–0 at home following a 70–63 win against Mercer. Cash a winning card with our free college basketball picks.

Game Information

  • Tipoff: 7:00 PM ET
  • Date: December 16, 2025
  • Where: Littlejohn Coliseum, Clemson, SC
  • TV: ESPN2

South Carolina Gamecocks

South Carolina averages 80.1 points per game and shoots 45.7% from the field as a team while hitting 31.3% from three-point range. Meechie Johnson is the leading scorer at 15.5 points per game and also leads the Gamecocks in assists at 3.3 per contest. Mike Sharavjamts is the second-leading scorer at 11.6 points per game and leads the team in rebounds at 6.6 while also pacing South Carolina with 0.8 blocks. Eli Ellis leads the team in steals at 0.9 per game.

Defensively, the Gamecocks allow 68.2 points per game and average 36.2 rebounds. South Carolina posts 2.5 blocks and 4.8 steals per contest, relying more on positioning than pressure. The Gamecocks enter this matchup on a two-game winning streak, but this will be their first road game against an opponent that has not lost at home this season.

Clemson Tigers

Clemson averages 81.8 points per game while shooting 45.5% from the field and 32.4% from beyond the arc. RJ Godfrey leads the Tigers with an average of 11.9 points per game and also tops the team in rebounds at 6.5 while adding a team-high 0.7 blocks. Jestin Porter is the second-leading scorer at 10.8 points per game, and Zac Foster leads the team in assists at 2.6 per contest. Dillon Hunter anchors the perimeter defense with a team-high 1.3 steals.

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The Tigers allow 66.4 points per game and control the glass with 41.4 rebounds per contest. Clemson averages 2.9 blocks and 5.8 steals, using rebounding and tough defense to limit second chances. The Tigers have been consistent at home, winning all six games at Littlejohn Coliseum this season.

South Carolina vs Clemson Prediction

South Carolina brings balanced scoring and solid defensive numbers, but Clemson’s rebounding advantage and defense at home create a difficult matchup for the Gamecocks in their first true road game. Clemson will control the boards and limit clean perimeter looks, resulting in the Tigers pulling away in the second half. Final Score Prediction: Clemson Tigers win and cover ATS, 77–68. Betting on sports and on South Carolina is easy, but even easier if you use the best sportsbooks. Make sure you know about how the fans are looking on prediction markets for Clemson with the social sportsbooks. Getting the most out of your bets on South Carolina vs Clemson can be done by using the Fanatics Sportsbook promo code.

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