Alabama vs. South Carolina Picks and Prediction for Saturday October 25, 2025

By: Dylan Hellebrand Updated 10/24/2025, 11:52 PM ET

On Saturday, the Alabama Crimson Tide (6-1) face off against the South Carolina Gamecocks (3-4) at Williams-Brice Stadium in Columbia, South Carolina. This game will be aired on ABC. Win or lose comes down to preparation—see today’s college football predictions from the experts.

Game Information for Alabama vs South Carolina

October 25, 2025
3:30pm EST
Williams-Brice Stadium, ABC
76° cloudy at start time

South Carolina Form & Recent Results

South Carolina heads into this matchup hoping to snap a two-game losing skid and reverse a rough stretch in which they've dropped four out of their last five games. Last week, the Gamecocks struggled in a 26-7 defeat against Oklahoma. Quarterback LaNorris Sellers completed 17 of 25 passes in that game, throwing for one touchdown. Over the course of the season, Sellers has accumulated 1,134 passing yards. On the ground, running back Rahsul Faison has contributed 281 rushing yards. The receiving corps is led by Vandrevius Jacobs, who has tallied 343 yards, along with Nyck Harbor, who has added 278 yards. Defensively, South Carolina has had trouble keeping opponents off the scoreboard lately, giving up an average of 23.8 points over their last five games. As the Gamecocks look to avoid picking up another conference loss, their offense will be aiming for improvement as well. South Carolina is scoring just 17.2 points per game this season.

Alabama Form & Recent Results

Alabama comes into this matchup riding a strong six-game winning streak, showing impressive consistency on the field. In their most recent game, they defeated Tennessee 37-20, thanks in part to a standout performance from quarterback Ty Simpson. Simpson completed 19 of his 29 passes and threw for two touchdowns, helping to guide the Crimson Tide to victory. Over the course of the season, Simpson has amassed 1,931 passing yards, demonstrating his ability as a leader for Alabama’s offense. On the ground, running back Jam Miller has contributed 282 rushing yards so far, providing a steady presence in the backfield. The team’s receiving corps features Germie Bernard, who leads with 472 receiving yards, and Ryan Williams, close behind with 423 yards. Both receivers have played crucial roles in keeping Alabama’s offense dynamic and difficult for defenses to handle. Over their last five games, the Crimson Tide have averaged 31.2 points per game, showing that their offense has found a reliable rhythm. When you look at the entire season, Alabama is putting up an average of 35.1 points per game. With this kind of offensive firepower, they’ll be aiming to extend their winning streak to seven games as they hit the field for their next challenge.

Key Players for the Crimson Tide and Gamecocks

Alabama QB Ty Simpson: 153/218, 18 TD, 1 INT
South Carolina QB LaNorris Sellers: 90/139, 5 TD, 2 INT

Betting Odds & Market Overview:

ALA -13.5; O/U 47.5

Alabama vs South Carolina Picks and Prediction

Since suffering a tough defeat to Florida State in week one, Alabama has bounced back in impressive fashion. Their offense has been firing on all cylinders, racking up points and overwhelming every team they've faced since then. Now, with their confidence restored and momentum on their side, the Crimson Tide are set to hit the road. They'll look to extend their winning streak and maintain their spotless record against conference rivals. Final Score Prediction, Alabama Crimson Tide win and cover the spread, 31-17.

Subscribe Now

I authorize Picks And Parlays to send me promotional emails

I understand that I can unsubscribe at any time. I have read and accepted the Terms & Conditions and Privacy Policy. I consent that Picks And Parlays may use third-party services to process my data.

Terms & Conditions