Arizona State vs Iowa State Picks and Prediction for Saturday November 1 2025

By: Eddie Kline Updated 10/31/2025, 08:18 PM ET

Arizona State Preview

Big 12 Conference foes will square off on Saturday, when the Arizona State Sun Devils invade Jack Trice Stadium to face the Iowa State Cyclones. Discover which teams the pros are backing with our daily college football picks. The Sun Devils (5-3) rank in the middle of the pack in total defense and are allowing 24.3 points per game. On Saturday, Arizona State played without leading WR Jordyn Tyson during a 24-16 home loss versus Houston.

Arizona State QB Sam Leavitt completed 18 of 35 passes for 270 yards and a three-yard touchdown pass to TE Cameron Harpole. Malik McClain caught seven passes for a season-high 159 yards in a losing effort for the Sun Devils, who committed 12 penalties for 76 yards.

Iowa State Preview

The Iowa State Cyclones started the season on a five-game winning streak, but are sitting at 2-3 in conference play. The Cyclones (5-3) rank eighth in the conference in total offense and are scoring 29.0 points per contest. Last week, Iowa State was unable to protect a 14-point lead during a 41-27 home loss versus 11th-ranked BYU.

Iowa State QB Rocco Becht was picked off three times, including one that returned for a score. Becht’s only touchdown pass was a 75-yard strike to Brett Eskildsen on the first offensive play from scrimmage. Carson Hansen rushed for 152 yards and two scores for the Cyclones.

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Arizona State vs Iowa State Pick

Arizona State QB Sam Leavitt was forced to leave Saturday’s loss with a lower leg injury and his status for this game is uncertain. With Leavitt and Tyson banged up, it is hard to imagine the Sun Devils finding a way to win in this spot. Take the Cyclones to cover at home. Final Score Prediction, Iowa State Cyclones win 31-20.