Arizona vs. Cincinnati Picks and Prediction for Saturday, November 15, 2025

By: Jake Allman Updated 11/15/2025, 12:18 AM ET

Arizona heads to Nippert Stadium for an early Big 12 kickoff against Cincinnati, with the Bearcats listed as 5.5-point home favorites and the total sitting at 56.5 on ESPN Bet. The Wildcats sit at 6-3 overall and 3-3 in conference play, while Cincinnati is 7-2 and pushing for a Big 12 title appearance. Kickoff is scheduled for 12:00 PM ET on FS1. Get the edge this weekend with our free college football picks backed by data and trends.

Arizona Outlook

Arizona enters off a narrow 24-20 win over Kansas, continuing its up-and-down conference season. Quarterback Noah Fifita has been steady, throwing for 2,042 yards with 21 touchdowns and only 4 interceptions on 65 percent passing. His accuracy has kept Arizona efficient even in tight games. Running back Ismail Mahdi contributes 530 rushing yards and 2 touchdowns, though the ground game has been inconsistent against stronger defensive fronts. Javin Whatley has emerged as the top target with 404 receiving yards and 4 scores, giving the Wildcats a reliable option in short-yardage situations. Linebacker Riley Wilson leads the pass rush with 3 sacks, and Dalton Johnson has a team-best 59 tackles.

Cincinnati Outlook

Cincinnati looks to bounce back after a 45-14 loss at Utah that ended a four-game win streak. Quarterback Brendan Sorsby continues to lead the Bearcats’ offense with 2,064 passing yards, 21 touchdowns, and just 2 interceptions—numbers that have kept the unit balanced and efficient. Tawee Walker has added 533 rushing yards and 4 touchdowns, helping Cincinnati control the tempo when ahead. Wideout Cyrus Allen has been the primary big-play threat, posting 514 yards and 10 touchdowns on only 36 receptions, a major factor in the Bearcats’ red-zone success. On defense, Jake Golday leads with 79 tackles and 3.5 sacks, giving Cincinnati a physical edge in the front seven. The group had been stout during its recent win streak before the setback in Salt Lake City.

Cincinnati vs Arizona Pick

Cincinnati has shown a more complete profile across both sides of the ball, especially at home, while Arizona’s road losses at Houston and Colorado raised concerns about consistency. If the Bearcats’ pass rush pressures Fifita early, the Wildcats could struggle to maintain pace. Expect a competitive first half, but Cincinnati’s balance and home-field advantage will prevail.

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Prediction: Cincinnati 34, Arizona 24