College Football Parlay For Saturday 11/15/25

By: Kim Smith Published 11/15/2025, 01:35 AM ET

The college football season has provided plenty of action all season long and it looks like it will provide even more action coming into this week of play. Now, these games have given us plenty of chance to find the best college football parlay for Saturday 11/15/25.

Check out our parlays, as well as all of our college football picks.

College Football Parlay

Arizona vs Cincinnati - Cincinnati -5.5 (-110)
Penn State vs Michigan State - Under 50.5 (-115)

Leg 1 - Arizona vs Cincinnati

Arizona is coming to this game here with a decent offense that can put up some serious scoring when they need to. Just look at the 33 points per game, but the Wildcats are a team that is converting only on 37% of the third downs, but also have a passing attack that sits at 254 yards a game and 151 on the ground. The Bearcats are coming to the game with an offense that is putting in 35.6 points per game, but has managed to get 241.4 yards in the air, but can easily ground out the clock with 195 yards per game on the ground. In this game here, I think the fatigue of a cross country flight coupled with the fact that the Wildcats are playing away from home will make it harder for the Arizona team to find the rhythm they are used to seeing on the offense that makes it easier to see the Bearcats win and cover this game. Make sure you check out the full Arizona vs Cincinnati prediction.

Leg 2 - Penn State vs Michigan State

Penn State is going to look to right their ship amid a long and lengthy losing skid. However, the Nittany Lions are facing a Michigan State team that has struggled just as much. However, in this game here I am not really looking at the teams to see which one will win the game. Instead, I am looking at the total in this game which is set at 50.5 points. This does look tempting figure, but if you look at the losing efforts for the teams recently the Spartans in their last loss only score 20 points and even in the loss to Michigan scored only 20 points. Penn State for their part have only managed to get 24 points in the last loss to Indiana and 14 against Ohio State. I look for this to continue as the offenses struggles and the under to be what hits in this game here. Check out the full Michigan State vs Penn State Prediction.

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A parlay is a great way to win quite a bit of money, but only if the parlay hits. In here I have provided my picks for a college football parlay for Saturday 11/15/25 and they have the potential to help you win quite a bit of money, but only if the picks hit.