College Football Parlay For Saturday 11/8/25

By: Kim Smith Published 11/08/2025, 01:45 AM ET

The college football season is definitely in full swing and a lot of the rivalry matches will be coming up soon. Until that time arrives, though, we will have to settle for a lot of the conference games that can help make or break a teams chances of the college football players. With that being said, we have found a couple of great games for a 2 team college football parlay for Saturday 11/8/25.

Check out our parlays, as well as all of our college football picks.

College Football Parlay

Indiana vs Penn State - Indiana Hoosiers -14.5 (Even)
Ohio State vs Purdue - Purdue Boilermakers +30.5 (-115)

Leg 1 - Indiana vs Penn State

This is a game that if Penn State played up to the hype would be one of the games that would be interesting to watch. Instead, Penn State has faltered on the year and the most hype they seem to be living up to lately is how quickly they can give up points. Indiana for their part has one of the most potent offenses on the year and are coming off of a blowout wins in back to back weeks that seen the final scores of 55-10 and 56-6. Meanwhile you have the Nittany Lions who have lost several close games, but when playing against Ohio State last week looked like a high school team facing the junior varsity of the worst team in the country. When facing a great offense the Penn State team has trouble stopping them and that is why I am taking the Indiana Hoosiers to win and cover. Check out the full Indiana vs Penn State prediction.

Leg 2 - Ohio State vs Purdue

The second leg of our parlay is Ohio State taking on Purdue. Do I think that the Buckeyes will win this game? Yes, I do think that the Ohio State team will win the game and do so easily. The big issue that I am looking at is the fact that the Buckeyes have been put at a 30.5 point favorite. Do I think the Buckeyes will cover that spread? No, and it is simply because outside of 2 games in their last 5 games the Buckeyes have not been able to cover that type of spread and one of those was only because the defense pitched a shut-out. What else does not help the Buckeyes cause here is the Boilermakers have been great at playing spoilers and have actually really upset the Buckeyes season in the past. Granted, losing on the spread will not upset the season, but an outright loss will and that shouldn't happen in this game. Still, with Purdue being able to keep the game close I see the Boilermakers covering the spread. Check out the Ohio State vs Purdue pick.

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A parlay is a great way to win quite a bit of money, but only if the parlay hits. In here I have provided my picks for a college football parlay for Saturday 11/8/25 and they have the potential to help you win quite a bit of money, but only if the picks hit.