Houston vs Oregon State Picks and Predictions for Friday, September 26, 2025

By: David Anicetti Published 09/21/2025, 01:54 PM ET

The Houston Cougars visit Reser Stadium to face the Oregon State Beavers on Friday, September 26, 2025, at 10:30 p.m. ET on ESPN. Houston is 3–0 after a 36–20 win over Colorado. Oregon State is 0–4 after a 41–7 loss at Oregon. Our free college football picks will build a nice bankroll.

Houston Preview

Quarterback Conner Weigman is off to a strong start: 569 yards, 4 touchdowns, and 0 interceptions. Weigman has talented targets. Stephon Johnson has speed with 6 receptions for 191 yards and one touchdown, with a long of 74 yards, and tight end Tanner Koziol and Amare Thomas have eight receptions for 110 yards and one touchdown. The run game is steady with Dean Connors (271 yards, 3 TDs) and Weigman (142 yards, 3 TDs). The line has given up only 6 sacks through three games.

On defense, Jalen Garner leads with 20 tackles. The secondary has produced takeaways—Wrook Brown (INT, 40 return yards) and Will James (INT, 37 return yards). The front seven has been active with 8 team sacks, helped by Corey Platt Jr., Eddie Walls III, and Brandon Mack II. Kicker Ethan Sanchez is 7-for-9 on field goals with a long of 52 yards.

Oregon State Preview

Quarterback Maalik Murphy has thrown for 964 yards with 6 touchdowns and 5 interceptions. Trent Walker leads the receivers (23 receptions, 302 yards), followed by Taz Reddicks (17 receptions, 240 yards) and David Wells Jr. (12 receptions, 170 yards). The run game has been solid: Anthony Hankerson has 228 yards and 2 TDs on 65 carries, but as a team average only 2.6 yards per rush. Protection is an issue with 6 sacks allowed.

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The Beavers’ defense needs more pressure. Team totals show only 3 sacks so far. Skyler Thomas and Dexter Foster pace the tackling with 31 each, and Jalil Tucker has the lone interception. Kicker Caleb Ojeda has range, hitting from 53 yards, but finishing drives remains one of the biggest problems.

Houston vs Oregon State Prediction

Houston has the stronger mix: a solid passing game, reliable running backs, and a defense that gets to the quarterback. Oregon State can hit a few deep throws, but Houston’s overall play and better deeper roster point to a road win. Final Score Prediction: Houston Cougars win and cover ATS 41-13.