James Madison vs Oregon Picks & Predictions for Saturday, December 20, 2025

By: Thomas Pemberton Published 12/14/2025, 11:28 PM ET

The Oregon Ducks will host the James Madison Dukes in the first round of the college football playoffs. Oregon is a -21.5 favorite and the over/under is set at 50.5 points. Kickoff is scheduled for 7:30 PM est at Autzen Stadium. Stay up to date with our expert's Free College Football Picks.ย 

James Madison Dukes Preview

The James Madison Dukes finished the regular season with a 12-1 record. The Dukes have won eleven straight games and carry a 5-1 road record. James Madison beat Troy 31-14 in their last game played. RB Wayne Knight rushed for 212 yards with a touchdown on 21 carries in the win. Knight has rushed for 1,263 yards this season on 190 carries. QB Alonza Barnett has 21 touchdowns and 8 interceptions on the season. James Madison is 5th best in the country averaging 245.8 rushing yards per game. The Dukes scored 37.3 points per game and allowed 15.8 points.

Oregon Ducks Preview

The Oregon Ducks are ranked 5th in the country. Oregon is 11-1 on the season with a 6-1 home field record. The Ducks are riding a six game win streak heading into the playoffs. Oregon beat Washington 26-14 in their last game played. QB Dante Moore threw for 286 yards and a touchdown in the win. Moore has 24 touchdowns and 6 interceptions on the season. Oregon is averaging 465 yards per game with 38.2 points scored. The Ducks are allowing 14.8 points per game.

James Madison vs Oregon Picks & Predictions

The Oregon Ducks are 7-4-1 against the spread on the season. While James Madison is 8-5 against the spread. The Dukes will come into this game very prepared but Oregon will be too much for them to compete with. Watch for the Ducks to be the better team but take all those free points with the barking underdog. Check out all the sportsbook promos to see if you are getting a great deal on your bets on James Madison. Make sure you know about how the fans are looking on prediction markets for Oregon with the Kickr promo code. Make sure when you place your bet on James Madison vs Oregon you are using the BetMGM bonus code.

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  • Final Score Prediction: Oregon Ducks win 38-28 but the James Madison Dukes cover ATS.

James Madison vs Oregon Best Free Picks

  • James Madison Dukesย +21.5
  • OVER 50.5
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