Kentucky vs Louisville Picks and Predictions for Saturday, November 29, 2025

By: Cameron Ross Published 11/25/2025, 11:58 PM ET

Kentucky vs Louisville Information

The Kentucky Wildcats will be on the road this week, playing the Louisville Cardinals at 12:00 PM in Louisville. Kentucky has five wins and six losses overall following a 28-point road loss to Vanderbilt last week to end a three-game winning streak. The Louisville Cardinals return home this week with seven wins and four losses, riding a three-game skid after a 32-point loss in Dallas to SMU. Stay in the action with our College Football Picks.

Kentucky Preview

Cutter Boley leads the Kentucky offense this season with 2060 yards and 15 scores on 185 completions. Seth McGowan is the top ball carrier on the team with 720 yards and 12 touchdowns on 163 carries. Dante Dowdell has added 106 carries for 530 yards and three scores. Kendrick Law is the top target on the team, leading the way with 524 yards and three touchdowns on 50 receptions this season. Betting on sports and on Kentucky is easy, but even easier if you use the best sportsbooks.

Louisville Preview

Miller Moss leads Louisville this season with 2344 yards and 11 touchdowns on 216 completions. Isaac Brown is the top ball carrier on the team with 782 yards and five touchdowns on 91 carries. Keyjuan Brown leads the team with 592 yards and six touchdowns on 81 carries. Chris Bell is the top receiver on the team with 72 catches for 917 yards and six scores. Make sure you know about how the fans are looking on prediction markets for Louisville with the Novig promo code.

Kentucky vs Louisville Prediction

Despite the recent struggles, Louisville is a better team in this matchup. Look for Louisville to write several of its wrongs this week as it ends the Kentucky season with a victory. Louisville was once a playoff contender before their recent losing streak and will finish the year on the right foot, punching their way into a top Bowl Game. Take Louisville to halt the Kentucky bowl hopes as the Cardinals get the winning cover Saturday at home. Final Score Prediction, Louisville Cardinals win and cover 30-21. Make sure when you place your bet on Kentucky vs Louisville you are using the BetMGM bonus code.

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