Massachusetts vs Missori Picks and Prediction for Saturday September 27 2025

By: Eddie Kline Updated 09/27/2025, 01:24 AM ET

Massachusetts Preview

In Saturday night college football action, the Massachusetts Minutemen travel to Memorial Stadium to face the Missouri Tigers. Saturday success begins with free college football picks you can rely on. The Minutemen (0-3) are playing their first season as a member of the MAC Conference and are surrendering 38.7 points per game. Last time out, Massachusetts managed just 119 yards of total offense during an ugly 47-7 road loss against Iowa.

Massachusetts scored their only touchdown early in the second quarter on a Grant Jordan six-yard run. The Minutemen rushing attack produced a woeful 27 yards on 26 attempts. LB Timmy Hinspeter recorded eight tackles and a sack.

Missouri Preview

The Missouri Tigers have won 21 games the last two seasons and are well on their way to their third consecutive double-digit win year. The 23rd ranked Tigers (4-0) rank third in the SEC Conference in total defense and are allowing 16.8 points per contest. On Saturday, Missouri scored the final 11 points to earn a 29-20 home victory versus South Carolina.

Missouri RB Ahmad Hardy led the way with a game-high 138 rushing yards and a score on 22 carries. Penn State transfer QB Beau Pribula threw for 171 yards and an eight-yard touchdown to Joshua Manning. The Tigers outgained the Gamecocks by a 458-293 margin.

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Massachusetts vs Missouri Pick

Massachusetts is producing a shade below 260 yards per game and it will be extremely difficult to come close to that in this spot. Missouri has a huge showdown with Alabama next week and will likely pull their starters early. Take the points with the Minutemen and hold your nose for 60 minutes. Final Score Prediction, Missouri Tigers win 40-15.