Michigan at Oklahoma Picks and Prediction September 6 2025

By: Dylan Hellebrand Published 09/01/2025, 09:16 PM ET

Michigan vs Oklahoma Game Info

On Saturday, the Michigan Wolverines (1-0) face off against the Oklahoma Sooners (1-0) at Memorial Stadium in Norman, Oklahoma. The game will be aired on ABC. Make sure you are ready for all the football action with our college football picks.

Oklahoma Preview

Oklahoma comes into this matchup having won their season opener. In their dominant 35-3 victory over Illinois State, Oklahoma’s quarterback John Mateer put together an impressive performance, completing 30 of his 37 pass attempts for 392 yards. He threw three touchdown passes but was intercepted once during the game. On the ground, running back Tory Blaylock contributed 44 rushing yards, while John Mateer added 24 rushing yards himself. Wide receiver Keontez Lewis was the top target, hauling in passes for a total of 119 receiving yards. The Sooners' defense has been solid, giving up an average of just 18.8 points per game over their last five matchups stretching back to last season. As they prepare for a major home showdown against a ranked Michigan squad, the defense’s recent form could be key. Last year, Oklahoma’s offense averaged 21.1 points per game, highlighting an area they may look to improve as they seek a statement win at home. Oklahoma enters this game as a 2.5 points favorite with the over/under total set at 46.5

Michigan Preview

Michigan enters this game having also won their season opener. In their 34-17 victory against New Mexico, Michigan's quarterback Bryce Underwood delivered an impressive performance, completing 21 of his 31 pass attempts for 251 yards and finding the end zone for one touchdown. The Wolverines also put up solid numbers in the run game, with running back Justice Haynes leading the charge with 159 rushing yards, while Jordan Marshall contributed 29 yards on the ground. In the passing attack, tight end Marlin Klein stood out as the top receiver, hauling in passes for a total of 93 receiving yards. Looking at Michigan's recent offensive production, the team has averaged 26.2 points per game over their last five games, dating back to last season. Last season, the Wolverines averaged 22 points per game. As Michigan prepares for a challenging road matchup against Oklahoma, they aim to keep improving their offensive output and strengthen their playoff credentials right from the outset this season.

Michigan vs Oklahoma Trends

Michigan was 1-3 on the road last season
The Wolverines averaged 14.2 points on the road
Oklahoma was 5-2 at home last season
The Sooners averaged 24.8 points at home

Michigan vs Oklahoma Pick

Both Michigan and Oklahoma enter this season with strong aspirations of making the playoffs, and this matchup marks the first significant challenge for both teams. Last year, Michigan faced some difficulties when playing away from home, often struggling to maintain their usual level of performance in hostile environments. In contrast, Oklahoma excelled when playing at their home stadium in Norman, consistently delivering impressive results in front of their fans. Final Score Prediction, Michigan Wolverines win 27-21.

Subscribe Now

I authorize Picks And Parlays to send me promotional emails

I understand that I can unsubscribe at any time. I have read and accepted the Terms & Conditions and Privacy Policy. I consent that Picks And Parlays may use third-party services to process my data.

Terms & Conditions