Michigan vs. Michigan State Picks and Prediction for Saturday, October 25, 2025

By: Jake Allman Published 10/25/2025, 12:05 AM ET

The rivalry between Michigan and Michigan State renews on Saturday in East Lansing, with the Wolverines coming in at 5–2 and the Spartans sitting at 3–4. Michigan bounced back from a road loss at USC by dominating Washington 24–7 last week, keeping its Big Ten title hopes alive. Michigan State, meanwhile, continues to search for answers after four straight conference defeats, most recently falling 38–13 at Indiana. The game kicks off from Spartan Stadium with crisp 44° weather expected. Rivalry week? Bowl season? Our college football predictions keep you ahead.

Michigan Preview

Michigan is built on being physical at the line of scrimmage. Quarterback Bryce Underwood has managed the offense effectively with 1,210 passing yards and five touchdowns to only two interceptions. Running back Justice Haynes has been the engine of the offense, rushing for 705 yards and eight scores on 95 carries. His ability to sustain drives will be key to keeping Michigan ahead on the road. The Wolverines’ strengths on both sides of the line have shown in recent wins, outscoring Wisconsin and Washington by a combined 48–17 while controlling time of possession. Linebacker Ernest Hausmann anchors the defense with 40 tackles, helping limit opponents to single-digit scoring in three of the last five games. If Michigan maintains that edge, it’ll dictate the tempo.

Michigan State Preview

Michigan State has faced a brutal stretch of competition, and it’s shown. The offense has struggled to stay consistent, averaging just 18 points per game across its last four outings. Quarterback Aidan Chiles has played well with 1,019 yards and nine touchdowns, but hasn’t had enough support in the run game, where Makhi Frazier’s 383 yards have been the bulk of the production. Omari Kelly remains a reliable option at receiver, totaling 347 yards on 24 catches, but the Spartans’ offensive line has been overwhelmed against talented defenses. On the other side, linebacker Jordan Hall leads the team with 45 tackles, and defensive back Malik Spencer has two sacks, but the unit has allowed 38 points in each of its last three contests. Improvement on third down is essential if Michigan State wants to hang around against a more complete Michigan squad.

Michigan vs Michigan State Prediction

Michigan’s recent dominance in this rivalry, combined with the current form of both teams, points strongly toward the Wolverines controlling this matchup. The Spartans’ inability to stop the run and generate consistent pressure will make it difficult to contain Haynes and Underwood’s attack. Expect Michigan to seize control early and lean on its defense to close out another convincing win.

Subscribe Now

I authorize Picks And Parlays to send me promotional emails

I understand that I can unsubscribe at any time. I have read and accepted the Terms & Conditions and Privacy Policy. I consent that Picks And Parlays may use third-party services to process my data.

Terms & Conditions

Prediction: Michigan 31, Michigan State 14