Nevada vs Wyoming Picks and Prediction for Saturday, November 22, 2025

By: Jake Allman Updated 11/22/2025, 01:37 AM ET

Nevada heads to Laramie sitting at 2–8 and 1–5 in the Mountain West, but the Wolf Pack finally showed some form last week with a 55–10 rout of San Jose State. Wyoming enters at 4–6 and 2–4 in conference play, and ESPN Analytics gives the Cowboys a 72.5 percent chance to win at home. Kickoff is at 4:00 p.m. ET on MWN at War Memorial Stadium, where the thin air and expected 40-degree temperatures often move games toward Wyoming’s style. From underdogs to point spreads, we’ve got your back with free college football picks.

Nevada Preview

Nevada’s offense has been a grind all season. Quarterback Carter Jones has thrown for 856 yards with 5 touchdowns and 8 interceptions, and the entire passing corps has combined for 9 touchdowns and 17 picks on the year. That turnover rate shows up every week and forces the Wolf Pack into difficult field position battles. The run game offers more reliability, with Caleb Ramseur delivering 500 yards at 4.8 yards per carry and 3 touchdowns. Nevada has spread the ball among several pass catchers, though tight end Jett Carpenter leads the team with 306 yards and one score.

There are solid defensive players scattered across this roster. Dylan Labarbera has piled up 76 tackles and 6.5 sacks and remains the most disruptive player up front. Jonathan Maldonado has added 5 sacks, and Murvin Kenion sits at 3 interceptions with 40 return yards. The problem is consistency. Nevada gave up 44 to San Diego State, 51 to Utah State, and 24 to New Mexico before dominating San Jose State. That swing makes handicapping the Wolf Pack tricky, but the overall season trends point toward vulnerability, especially on the road. Make sure you know about how the fans are looking on prediction markets for Nevada with the Thrillz promo code.

Wyoming Preview

Wyoming’s offense is steadier and fits the environment in Laramie. Kaden Anderson has thrown for 1,791 yards with 11 touchdowns and 10 interceptions, and although that stat line is not perfect, it still provides more structure than Nevada’s passing attack. The Cowboys rely heavily on the backfield, rushing for 1,458 yards at 4.3 per carry. Samuel Harris leads with 546 yards, while Terron Kellman and Sam Scott have combined for 683 yards and six touchdowns. Chris Durr Jr. gives Anderson a reliable outside threat, posting 435 yards and 4 touchdowns with strong yards-after-catch production.

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Wyoming has shown more balance on defense as well. Linebacker Brayden Johnson leads with 62 tackles, Evan Eller adds 58 tackles and 2 sacks, and Ben Florentine is a force inside with 5 sacks. The Cowboys generate pressure in key moments, and safety Desman Hearns can capitalize on bad throws, owning 2 interceptions. This group had a shutout against Colorado State and kept Air Force’s option attack below its averages. Make the most of your bets on Wyoming by using the sportsbook promos.

Wyoming vs Nevada Pick

Prediction: Wyoming 27, Nevada 17. Wyoming - spread. Lean to the under based on both teams’ run-heavy tendencies and Nevada’s turnover issues slowing drives. Make sure when you place your Nevada vs Wyoming bet you are using the bet365 bonus code.