Notre Dame vs. Pittsburgh Picks and Prediction for Saturday, November 15, 2025

By: Jake Allman Updated 11/15/2025, 12:18 AM ET

Notre Dame heads to Pittsburgh for an ACC showdown between two 7-2 teams with postseason implications. Kickoff is set for 12:00 PM ET at Acrisure Stadium, airing on ABC. The Fighting Irish enter as 11.5-point favorites, with the total at 56.5 points according to ESPN Bet. Get the edge this weekend with our free college football picks backed by data and trends.

Notre Dame Analysis

Notre Dame is riding a five-game winning streak and has looked sharp on both sides of the ball, outscoring opponents 172-58 over that stretch. Freshman quarterback CJ Carr continues to settle into his role with 2,057 yards and 16 touchdowns to only four interceptions. His chemistry with Jordan Faison, who leads the team with 518 receiving yards, gives the Irish consistency in the short-to-intermediate passing game. The run game is the foundation, though, with Jeremiyah Love racking up 894 yards and 11 scores on 141 carries. The Irish offense has thrived on balance, averaging strong production per drive and limiting turnovers. Boubacar Traore has become the leader up front with 6.5 sacks, and linebacker Drayk Bowen anchors the middle with 50 tackles. Notre Dame has excelled at containing explosive plays, allowing just 11 points per game over the last month.

Pittsburgh Analysis

Pittsburgh has been equally impressive, winning five straight, including road wins over Florida State and Syracuse. Quarterback Mason Heintschel has thrown for 1,547 yards and 12 touchdowns, managing games efficiently behind a solid offensive line. The Panthers rely heavily on Ja’Kyrian Turner, who’s totaled 399 yards and six touchdowns, to set up play-action opportunities. Kenny Johnson has become Heintschel’s top target with 573 receiving yards and four touchdowns, stretching the field with his speed. Linebacker Braylan Lovelace leads the team with 55 tackles, while Jimmy Scott has contributed four sacks. Pittsburgh’s defense is opportunistic but has struggled to slow down balanced attacks, allowing over 30 points twice in the past month despite steady offensive output.

Notre Dame vs Pittsburgh Prediction

Notre Dame’s size and depth on both lines make it the more complete team entering this matchup. The Irish have been disciplined, efficient, and dominant in the trenches, which should translate well against a Pittsburgh defense that’s been vulnerable against strong rushing units. With Carr’s accuracy and Love’s ground game, expect Notre Dame to control the tempo early and wear down the Panthers by the fourth quarter.

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Prediction: Notre Dame 34, Pittsburgh 20