Ohio State vs Ohio Picks and Predictions for Saturday September 13 2025

By: Jeremy O'Quinn Published 09/08/2025, 02:22 AM ET

Ohio State Preview

The Ohio State Buckeyes are heading to Ohio Stadium in week three of college football, where they will face the Ohio Bobcats. Get the rest of our free NCAAF picks here! The Ohio State Buckeyes sit 2-0, ranked as number one team in the nation. The Buckeyes opened the season with a statement, knocking off then-number 1 team Texas in a 14โ€“7 defensive battle in Austin. Quarterback Julian Sayin was efficient in his first true test, completing 13 of 20 passes for 126 yards and a touchdown, while wide receiver Carnell Tate delivered a clutch fourth-quarter score. In Week 2, Ohio State cruised to a blowout win over Kent State, giving the starters valuable reps before turning the focus to this in-state matchup.

Ohio Preview

The Ohio Bobcats currently sit 1-1 in the MAC after an up-and-down start to their 2025 campaign. Ohio opened with a tough 34โ€“31 road loss at Rutgers, a game where the Bobcats showed offensive flashes but couldnโ€™t finish drives consistently. They bounced back in Week 2 with a headline-grabbing 17โ€“10 upset over West Virginia in Athens, marking one of the programโ€™s biggest wins in recent years. Quarterback Parker Navarro showcased his dual-threat ability, combining for 247 passing yards and 87 rushing yards to pace the Bobcatsโ€™ offense. Wideout Chase Hendricks was the go-to target, racking up 121 receiving yards and a touchdown, while the Bobcatsโ€™ defense came up with timely stops to seal the win.

Ohio State vs Ohio Pick

The Bobcats proved that they can compete against Power Five teams, however this Buckeyes team is on a whole different level. Expect Ohio State to comfortably take this game on the road, covering the -32.5 spread while doing so. Final score prediction, Ohio State wins 49-15.

Betting on College Football?

Onyx Odds

Spend $10 Get 200 in Bonus Picks

Show Bonus Code
Claim Bonus
Signup Promo Recommended Onyx Odds Bonus
Can be redeemed Yes
betr

$200 in No Sweat Entries + A Free Pick

Show Bonus Code
Claim Bonus
Signup Promo Hot Offer
Min. Purchase $10
Requirement $200 Betr Bucks maximum per user ($100 from each Qualifying Entry token)
Playthrough 1x Bonus
Can be redeemed Yes
Thrillzz

Get 100% on any coins purchase up to $100

Show Bonus Code
Claim Bonus
Signup Promo Hot Offer Thrillzz Bonus
Can be redeemed Yes
Video: Today's MLB BEST Bets: Brewers vs Padres + Royals vs Dodgers Picks and Predictions
Today's MLB BEST Bets: Brewers vs Padres + Royals vs Dodgers Picks and Predictions
Video: Daily Profit: Can The Seahawks REPEAT?? NFC West Betting Preview
Daily Profit: Can The Seahawks REPEAT?? NFC West Betting Preview

Sign Up Get $30 Premium Picks Credit + Exclusive Offers

Subscribe Now

I understand that I can unsubscribe at any time. I have read and accepted the Terms & Conditions and Privacy Policy. I consent that Picks And Parlays may use third-party services to process my data.
logo

If you or someone you know has a gambling problem, crisis counseling and referral services can be accessed by calling 1-800-GAMBLER (1-800-426-2537) (IL). Gambling problem? Call 1-800-GAMBLER (MI/NJ/PA/WV/WY), 1-800-9-WITH-IT (IN), 1-800-522-4700 (CO), 1-800-BETS OFF (IA), 1-888-532-3500 (VA), 1-800-NEXT STEP (AZ), or call/text TN REDLINE 1-800-889-9789 (TN). 21+ (18+ WY). AZ/CO/IL/IN/IA/MI/NJ/PA/TN/VA/WV/WY only. Eligibility restrictions apply. T&C's Apply. Void where prohibited. If you click on a link on this site which takes you to a bookmaker or casino and you subsequently open an account, Pick and Parlays may receive a commission. Bets placed are the responsibility of the bettor.

Copyright ยฉ 2026 Picks and Parlays. All rights reserved.

The sports news and information contained at this site is for entertainment purposes only. Any use of this information in violation of laws whether they are federal, state and/or local is prohibited. Picks and Parlays is the nation's premier resource for sports betting and handicapping information.

Sign Up Get $30 Premium Picks Credit + Exclusive Offers
Special Offer
Spend $10 Get 200 in Bonus Picks
Play now T&Cs apply, 18+