Penn State vs UCLA Picks and Prediction for Saturday October 4 2025

By: Eddie Kline Updated 10/03/2025, 11:09 PM ET

Penn State Preview

The historic Rose Bowl will be the setting on Saturday afternoon for a Big Ten Conference battle between the Penn State Nittany Lions and the UCLA Bruins. Maximize your wagers by reading our free college football picks before kickoff. The seventh-ranked Nittany Lions (3-1) were the preseason betting favorites to win the National Championship and are allowing 11.8 points per game. On Saturday, Penn State went to double overtime with visiting Oregon before falling by a 30-24 final score.

Penn State trailed 17-3 in the fourth quarter before rallying to tie the score on a pair of Devonte Ross touchdown receptions. Kaytron Allen gave the Nittany Lions a 24-17 advantage in the first overtime on a four-yard touchdown run. Penn State managed just 276 yards and turned the ball over once.

UCLA Preview

The UCLA Bruins are the only winless team in the Big Ten Conference and replaced head coach DeShaun Foster with Tim Skipper on an interim basis. The Bruins (0-4) rank last in the conference in total offense and are scoring a measly 14.3 points per contest. Last week, UCLA held host Northwestern scoreless over the final 33 minutes of a disappointing 17-14 road loss.

Mateen Bhaghani nailed two field goals to cap a pair of UCLA scoring drives that went for 70 plus yards. Tennessee transfer QB Nico Iamaleava threw a 29-yard touchdown to Kwazi Gilmer. Iamaleava added a team high 65 rushing yards for the Bruins.

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Penn State vs UCLA Pick

Penn State will be deflated emotionally after having their comeback fall short against Oregon. The Nittany Lions are elite on the defensive side of the ball and will have no problem getting after UCLA QB Nico Iamaleava. Look for Penn State to win easily on the road in a game that stays under the total. Final Score Prediction, Penn State Nittany Lions win 34-10.