Rutgers vs Ohio State Picks and Predictions for Saturday, November 22, 2025

By: David Anicetti Updated 11/22/2025, 01:31 AM ET

Rutgers (5–5, 2–5 Big Ten) travels to Columbus to face Ohio State (10–0, 7–0 Big Ten) in a late-season conference matchup. Rutgers is coming off a 35–20 win over Maryland, but has also dropped three of its last five. Ohio State continues to control the Big Ten, winning all 10 games and each of its first seven conference outings. Looking for today’s college football picks? Don’t miss our expert breakdowns.

Game Information for Rutgers vs Ohio State

Kickoff: 1:00 PM EST, November 22
Where: Ohio Stadium, Columbus, OH
TV: ABC

Rutgers Preview

Rutgers is led by quarterback Athan Kaliakmanis, who has thrown for 2,705 yards with 17 touchdowns and seven interceptions. His top target is KJ Duff, who leads the team with 923 receiving yards and six touchdowns. Rutgers has relied on running back Antwan Raymond on the ground, as he has reached 1,000 rushing yards with 11 touchdowns.

On defense, Rutgers relies on Jett Elad, who leads the team with 59 tackles and two interceptions.. Over the last month, Rutgers has allowed 35 points to Maryland, 38 to Washington, and 56 to Oregon, with big-yardage plays becoming a recurring issue. The front has moments of pressure with Eric O’Neill and Bradley Weaver, but consistency has been a problem. Betting on sports and on Rutgers is easy, but even easier if you use the best sportsbooks.

Ohio State Preview

Ohio State continues to be led by quarterback Julian Sayin, who has thrown for 2,491 yards with 24 touchdowns and only four interceptions while completing over 80% of his passes. His main weapon is Jeremiah Smith, who has 862 yards and 10 touchdowns, and Carnell Tate has added 711 yards and seven scores. The run game also contributes, with Bo Jackson at 613 rushing yards and CJ Donaldson producing nine rushing touchdowns. Ohio State has moved the ball well in every matchup.

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The Buckeyes’ defense has been just as strong. Arvell Reese leads the team with 55 tackles and 6.5 sacks, while Caden Curry has added 7.0 sacks off the edge. Caleb Downs controls the secondary and has two interceptions. Ohio State has held each of its last five opponents to 16 points or fewer. Make sure you know about how the fans are looking on prediction markets for Ohio State with the Novig promo code.

Rutgers vs Ohio State Prediction

Rutgers has playmakers in Duff and Raymond, but matching Ohio State on the road is a tough assignment. Sayin and the receivers will find openings early, and the Buckeyes’ front seven has dominated every recent opponent. Final Score Prediction: Ohio State Buckeyes win and cover ATS, 45–7. Make sure when you place your bet on Rutgers vs Ohio State you are using the BetMGM bonus code.