Southern Miss vs Louisiana Tech Pick and Prediction for Saturday, September 20, 2025

By: Cameron Ross Published 09/15/2025, 12:25 AM ET

Southern Miss vs Louisiana Tech Information

The Southern Miss Golden Eagles will be on the road again for the first time this season this week with a game in Joe Aillet Stadium against the Louisiana Tech Bulldogs at 7:30 PM. Southern Miss has two wins and one loss on the year, riding a 2-game winning streak into this matchup following a double-digit victory against Appalachian State. The Louisiana Tech Bulldogs stay home this week with two wins and one loss after a 35-point blowout of New Mexico State a week ago. Stay in the action with our College Football Picks.

Southern Miss Preview

The Southern Golden Eagles have been strong on the offensive side this season, scoring 31 points per game, and have scored 38 points in each of their two victories. Defensively, Southern Miss has been mediocre, allowing 25.3 points per game through three games played. Braylon Braxton leads the Southern Miss offense this season with 692 yards and seven scores on 68 completions. Jeffrey Pittman is the top ball carrier on the team with 126 yards and two scores on 25 carries. Elijah Metcalf leads the team with 10 catches for 124 yards.

Louisiana Tech Preview

The Louisiana Tech Bulldogs have been stout on the offensive side this season, averaging 26.6 points per game overall. Defensively, Louisiana Tech has been strong, holding opponents to just 12.33 points per game. Blake Baker leads Louisiana Tech this season with 228 yards and two scores on 11 completions. Trey Kukuk has shifted heavily with 28 completions for 224 yards and two scores. Clay Thevenin is the top ball carrier on the team with 24 carries for 151 yards and one score. Devin Gandy leads the team with three catches for 78 yards and one touchdown.

Southern Miss vs Louisiana Tech Prediction

Both teams come into this game with the same record, but Louisiana Tech is in the better spot. The Bulldogs are stronger on both sides of the ball, and that will be the difference this week. Take Louisiana Tech to overwhelm a good Southern Miss team for 60 minutes Saturday, leading to the win and cover at home. Final Score Prediction, Louisiana Tech Bulldogs win and cover 41-31.

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Best Picks:

ยทย ย ย ย ย  Louisiana Tech Bulldogs -2.5

ยทย ย ย ย ย  Over 51.5

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