Tulane vs Ole Miss Picks & Predictions for Saturday, December 20, 2025

By: Thomas Pemberton Published 12/14/2025, 11:19 PM ET

The Tulane Green Wave head to Ole Miss to take on the Rebels for the first round of the College Football Playoff. Kickoff is scheduled for 3:30 PM est at Vaught-Hemingway Stadium. Ole Miss is a -17.5 favorite and the over/under is set at 56.5 points. Stay up to date with our expert's Free College Football Picks. 

Tulane Green Wave Preview

The Tulane Green Wave finished the regular season as the 20th ranked team. Tulane is 11-2 on the season with a 4-2 road record. The Green Wave head into the college playoffs riding a five game win streak. Tulane beat North Texas 34-21 in their last game. RB Jamauri McClure led the offense with 121 rushing yards and a touchdown on 22 carries. QB Jake Retzlaff has 14 passing touchdowns, 6 interceptions, and 16 rushing touchdowns on the season. Tulane is averaging 410 yards per game with 29.1 points scored. The Green Wave are allowing 22.6 points per game.

Ole Miss Rebels Preview

The Ole Miss Rebels are ranked #6 in the country. Ole Miss went 11-1 on the season with a 8-0 home field record. The Rebels head into the playoffs riding a five game win streak. Ole Miss beat Mississippi State 38-19 in their last game played. QB Trinidad Chambliss threw for 359 yards and 4 touchdowns in the win. Chambliss has 18 touchdowns and 3 interceptions on the season. Ole Miss ranks 3rd best in the country with 498 yards of offense per game. The Rebels are scoring 37.3 points per game while allowing 20.1 points per game.

Tulane vs Ole Miss Picks & Predictions

The Ole Miss Rebels beat up on Tulane 45-10 earlier this season. Both Ole Miss and Tulane have covered the spread in seven games this season. The Rebels carry an unbeaten home record and look to be the better team on both sides of the ball. Watch for Ole Miss to control this game. Lay the points. Check out all the sportsbook promos to see if you are getting a great deal on your bets on Tulane. Make sure you know about how the fans are looking on prediction markets for Ole Miss with the Kickr promo code. Make sure when you place your bet on Ole Miss vs Tulane you are using the BetMGM bonus code.

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  • Final Score Prediction: Ole Miss Rebels win 34-13 and cover ATS.

Tulane vs Ole Miss Best Free Picks

  • Ole Miss Rebels -17.5
  • UNDER 56.5
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