Vanderbilt vs Tennessee Picks and Prediction for Saturday November 29 2025

By: Eddie Kline Published 11/24/2025, 12:53 AM ET

Vanderbilt Preview

In-State rivals will square off on Saturday afternoon, when the Vanderbilt Commodores invade Neyland Stadium to take on the Tennessee Volunteers. Make sure you are ready for all the football action with our college football picks. The 14th ranked Commodores (9-2) have split their first four road games and would likely secure a College Football Playoff spot with a win. On Saturday, Vanderbilt outscored Kentucky by 21 points in the third quarter to run away with a 45-17 home victory.

Vanderbilt QB Diego Pavia made a major Heisman Trophy statement with a career-high 484 passing yards and six total touchdowns. Tre Richardson caught six passes for 159 yards and found the end zone three times. The Commodores rolled up 604 yards of total offense and forced three turnovers. The best sportsbooks are the best way to go when you are betting on Vanderbilt.

Tennessee Preview

The Tennessee Volunteers have won four of their six home games and are winless in their three contests versus ranked opponents. The Volunteers (8-3) rank second in the SEC Conference in total offense and are scoring 42.3 points per contest. On Saturday, Tennessee raced out to a 14-point lead after one quarter and never looked back during a 31-11 road triumph against Florida.

Tennessee QB Joey Aquilar was an efficient 17-for-22 passing for 204 yards and a 23-yard touchdown pass to Ethan Davis. DeSean Bishop contributed 116 rushing yards and two scores for the Volunteers, who possessed the ball for more than 35 minutes. Make sure you know about how the fans are looking on prediction markets for Tennessee with the Onyx Odds promo code.

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Vanderbilt vs Tennessee Pick

Tennessee has defeated Vanderbilt in four straight seasons, including last year’s 36-23 victory in Nashville. These two programs have plenty of offensive firepower, so the over is worth a look. The stronger play is on the Commodores to pull off the upset behind another strong performance from Pavia. Final Score Prediction, Vanderbilt Commodores win 35-31. Getting the most out of your bets on Vanderbilt vs Tennessee can be done by using the Fanatics Sportsbook promo code.