Virginia vs North Carolina Picks & Predictions for Saturday, October 25, 2025

By: Thomas Pemberton Updated 10/25/2025, 12:00 AM ET

The North Carolina Tar Heels will host the Virginia Cavaliers this weekend. North Carolina is a +9.5 home underdog and the over/under is set at 52.5 points. The Tar Heels beat the Cavaliers 41-14 in their last meeting last season. Kickoff is scheduled for 12:00 PM est at Kenan Stadium. Stay ahead of the oddsmakers with insider-level college football predictions.

Virginia Cavaliers Preview

The Virginia Cavaliers are 6-1 on the season. Virginia is riding a five game win streak and they carry a 1-1 road record. The Cavaliers are 5-1 against the spread on the season. Virginia has some impressive wins this season as they have beat Florida State, Stanford, and Louisivlle. The Cavaliers beat Washington State in their last game played 22-20. QB Chandler Morris threw for 179 yards. Morris has 11 passing touchdowns on the season with 4 interceptions. Virginia is averaging 40 points scored per game which is 10th best in the country.

North Carolina Tar Heels Preview

The North Carolina Tar Heels are 2-4 on the season. North Carolina is riding a three game losing streak and they carry a 1-2 home field record. The Tar Heels haven't scored more than 21 points in any of their last three games. North Carolina lost to California in their last game 21-18. QB Gio Lopez threw for 167 yards. Lopez has 3 passing touchdowns with 3 interceptions on the season. North Carolina is 3-3 against the spread on the season. The Tar Heels are averaging 18.7 points scored per game.

Virginia vs North Carolina Picks and Predictions

Virginia and North Carolina are trending in opposite directions. The Cavaliers are looking to win their sixth straight game. While North Carolina is in jeopardy of losing their fourth straight game. Virginia is the better team even on the road in this matchup. Watch for the Tar Heels offensive to struggle to keep pace with the Cavaliers.

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Final Score Prediction: Virginia Cavaliers win and cover ATS 34-17.