Wake Forest vs. Virginia Tech Picks and Prediction for Saturday, October 4, 2025

By: Jake Allman Updated 10/03/2025, 11:15 PM ET

Wake Forest vs Virginia Game Information

Wake Forest heads to Blacksburg looking to rebound from a heartbreaking overtime loss to Georgia Tech, while Virginia Tech tries to build momentum off a narrow road win against NC State. The Demon Deacons sit at 2-2 overall and winless in ACC play, while the Hokies are 2-3 but already 1-0 in the league. This matchup kicks off at 1:00 p.m. ET from Lane Stadium and will be broadcast on The CW Network. Rivalry week? Bowl season? Looking to cash in this weekend? Start with our trusted college football picks.

Wake Forest Preview

Wake Forest’s offense has struggled to find consistency through four games. Quarterback Robby Ashford has thrown for 916 yards but has just one touchdown against three interceptions. Running back Demond Claiborne has been more reliable with 366 yards and six touchdowns on just 46 carries, giving the Deacons a needed spark on the ground. Chris Barnes leads the receiving corps with 287 yards on 15 catches, though Wake Forest hasn’t been able to consistently stretch defenses vertically. The team is coming off a tough 30-29 overtime loss to Georgia Tech, where execution late cost them.

Virginia Tech Preview

Virginia Tech comes in with momentum after edging NC State 23-21. Quarterback Kyron Drones has been efficient with 1,105 passing yards, eight touchdowns, and only three interceptions. The run game has featured Terion Stewart, who averages over nine yards per carry with 239 yards on just 26 attempts. Ayden Greene has been a steady target with 244 receiving yards and a touchdown. On the defensive side, Virginia Tech has benefited from impact plays from Langston Hardy, who has 2.5 sacks, and safety Isaiah Cash, who leads the unit with 25 tackles. The Hokies have looked sharper in the last two outings, especially with a decisive 38-6 win over Wofford earlier in September.

Virginia Tech vs Wake Forest Prediction

Prediction leans toward Virginia Tech having the upper hand thanks to more balance offensively and a home-field edge. Wake Forest has shown they can run the ball effectively, but the lack of passing production makes it hard to match up with the Hokies’ improved attack. Expect Virginia Tech to control the pace with Drones making enough plays through the air to complement Stewart on the ground. The Hokies’ defense should keep Wake Forest in check, while the offense will control the ball and score enough to cover.

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Final Score Prediction: Virginia Tech 31, Wake Forest 20

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Best Bets:

  • Virginia Tech -7.5
  • Under 55.5 Total Points.
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