Arizona Cardinals vs Tampa Bay Buccaneers Picks and Predictions for Sunday, November 30, 2025

By: David Anicetti Published 11/24/2025, 09:23 PM ET

The Arizona Cardinals visit the Tampa Bay Buccaneers on Sunday. Arizona is 3–8 (fourth in the NFC West) after a 27–24 overtime loss to Jacksonville. Tampa Bay is 6–5 (second in the NFC South) following a 34–7 loss to the Rams. Build your bankroll using our NFL picks.

Cardinals vs Buccaneers Game Information

Kickoff: 1:00 PM ET
Date: November 30
Where: Raymond James Stadium, Tampa, FL
TV: FOX

Team Breakdown - Arizona Cardinals

Jacoby Brissett leads Arizona with 1,887 passing yards, 11 touchdowns, and three interceptions while completing 66.8 percent of his attempts, but is questionable for Sunday’s game. If Brissett is unable to play, the Cards will turn to Kedon Slovis. The Cardinals average 256.3 passing yards and 101.1 rushing yards per game, highlighted by Emari Demercado’s 241 rushing yards and Trey McBride’s 797 receiving yards and seven touchdowns. Over the last five games, Arizona has scored an average of 23.6 points per game.

Budda Baker leads the defense with 78 tackles, while Dadrion Taylor-Demerson tops the team with two interceptions. Josh Sweat has nine sacks, contributing to 22 total sacks and nine interceptions. The Cardinals have allowed 31.2 points per game across their last five. Betting on sports and on the Cardinals is easy, but even easier if you use the best sportsbooks.

Team Breakdown - Tampa Bay Buccaneers

Baker Mayfield directs Tampa Bay’s offense with 2,406 passing yards, 18 touchdowns, and five interceptions, completing 62.7% of his passes, but he injured his shoulder in Sunday’s loss and is questionable. The Buccaneers average 224.4 passing yards and 111.2 rushing yards per game. Rachaad White leads the ground game with 414 rushing yards, while Emeka Egbuka has 749 receiving yards and six touchdowns. Over the last five games, Tampa Bay has scored an average of 18.8 points per game.

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Tykee Smith leads the defense with 85 tackles, and Jamel Dean has a team-high three interceptions. Yaya Diaby’s five sacks pace a defense that has recorded 27 quarterback sacks and made 10 interceptions. The Buccaneers have allowed 26.6 points per game in the last five outings, and their pass-rush is a key to their success. Make sure you know about how the fans are looking on prediction markets for the Buccaneers with the Novig promo code.

Arizona Cardinals vs Tampa Bay Buccaneers Prediction

Tampa Bay’s combination of quarterback production, takeaways, and pressure defense will be what helps the Bucs win. Arizona can move the ball with passes to McBride, but the Buccaneers will make more stops on defense and score behind Mayfield or backup Teddy Bridgewater. Final Score Prediction: Tampa Bay Buccaneers win and cover ATS, 27–21. Make sure when you place your bet on Cardinals vs Buccaneers you are using the BetMGM bonus code.