Dallas Cowboys vs. Denver Broncos Picks and Prediction for Sunday, October 26, 2025

By: Jake Allman Published 10/20/2025, 09:48 PM ET

The Dallas Cowboys travel to Denver on Sunday afternoon to face the Broncos at Empower Field at Mile High. Kickoff is scheduled for 4:25 PM ET on CBS. Dallas sits at 3-3-1 after a blowout win over Washington, while Denver has surged to 5-2 thanks to four straight victories, including a 33-32 win over the Giants last Sunday. ESPN Analytics gives the Broncos a 56.7% chance to win, and the spread favors Denver by 2.5 points with a total of 49.5. From underdogs to point spreads, we’ve got the sharpest NFL picks.

Cowboys Preview

Dak Prescott has been the key to success for Dallas, throwing for 1,881 yards with 16 touchdowns and only three interceptions through seven games. His connection with George Pickens has been the centerpiece of the offense, as Pickens leads the team with 607 yards and six touchdowns. The Cowboys’ ground game has also contributed significantly, with Javonte Williams posting 592 yards and six scores on 111 carries. However, inconsistency on the road has hurt the Cowboys, with Dallas just 1-3 away from home. The pass rush has been strong behind James Houston’s 3.5 sacks, but key injuries to linemen like Kenny Clark and Marshawn Kneeland could affect pressure against Bo Nix.

Broncos Preview

Denver’s rise behind Bo Nix has been one of the AFC’s early storylines. Nix has thrown for 1,556 yards and 11 touchdowns, spreading the ball effectively across multiple targets. Courtland Sutton has been Nix’s top target with 469 yards and three scores, while J.K. Dobbins has powered the run game with 523 yards and four touchdowns. The Broncos’ pass protection has been strong, allowing Nix to remain in the pocket. Linebacker Nik Bonitto has been the defensive leader, with eight sacks to anchor a front. Denver’s defense has also stepped up of late, holding the Jets to just 11 points and forcing turnovers in key moments.

Broncos vs Cowboys Prediction

The altitude and defensive strengths give Denver an advantage, especially against a Cowboys team that has struggled away from AT&T Stadium. Prescott and the passing attack will keep this close, but Nix’s consistency and the Broncos’ balance on both sides of the line of scrimmage will prevail in the end.

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Prediction: Broncos 27, Cowboys 23