Los Angeles Chargers at Jacksonville Jaguars Picks and Predictions for Sunday, November 16, 2025

By: David Anicetti Published 11/11/2025, 07:52 PM ET

The Los Angeles Chargers visit the Jacksonville Jaguars on Sunday at EverBank Stadium. Los Angeles is 7–3 and second in the AFC West after a 25–10 win over Pittsburgh. Jacksonville is 5–4 and second in the AFC South following a 36–29 loss at Houston. Check our NFL picks before kickoff.

Chargers vs Jaguars Game Demographics

Date: Sunday, November 16

Time: 1:00 PM ET

Where: EverBank Stadium, Jacksonville, Florida

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TV: CBS

Breaking Down The Los Angeles Chargers

Quarterback Justin Herbert is 240-of-358 for 2,610 yards with 19 touchdowns and eight interceptions, averaging 261.0 passing yards per game. Kimani Vidal leads the rushing attack with 404 yards and two touchdowns on 91 carries. Ladd McConkey is the top receiver with 51 receptions for 631 yards and four touchdowns, and Keenan Allen adds 52 catches for 539 yards and four scores. Make sure you know about how the fans are looking on social for the Chargers with the Fliff promo code.

Linebacker Daiyan Henley leads the defense with 67 tackles. Safety Tony Jefferson leads in interceptions with two. Edge rusher Tuli Tuipulotu has eight sacks, giving Los Angeles steady pressure in passing situations. The Chargers have won four of five and have tightened red-zone defense while cutting down penalties, supporting a pass game that continues to produce.

Breaking Down The Jacksonville Jaguars

Quarterback Trevor Lawrence is 188-of-316 for 1,998 yards with 10 touchdowns and seven interceptions, averaging 222.0 passing yards per game. Travis Etienne Jr. leads the ground game with 656 yards and three touchdowns on 135 carries. Brian Thomas Jr. leads in receiving with 30 catches for 420 yards, but is inactive (ankle); Parker Washington has 28 receptions for 330 yards and two touchdowns.

Linebacker Foyesade Oluokun leads the defense with 75 tackles. Linebacker Devin Lloyd leads in interceptions with four. Jacksonville’s front has generated pressure with Arik Armstead at 4.5 sacks, and the secondary has produced takeaways, but recent third-down stops have dropped, creating longer drives for opponents. Make the most of your bets on the Jaguars by using the sportsbook promos.

Los Angeles Chargers at Jacksonville Jaguars Prediction

Los Angeles brings the better passing game with Herbert, McConkey, and Allen producing strong gains, while Jacksonville relies on Etienne’s workload and shorter throws from Lawrence. With Thomas unavailable, the defense will double Parker Washington, and the Chargers’ pass rush can bother Lawrence. Final Score Prediction: Los Angeles Chargers win and cover ATS, 28–23. Make sure when you place your Chargers vs Jaguars bet you are using the bet365 bonus code.