Minnesota Vikings vs Los Angeles Chargers Picks and Prediction for Thursday October 23 2025

By: Eddie Kline Published 10/20/2025, 10:38 PM ET

Vikings Preview

The week eight NFL schedule will kick off on Thursday night with a battle between the Minnesota Vikings and the Los Angeles Chargers from beautiful SoFi Stadium. Get ready for all the football action with our NFL Picks. The Vikings (3-3) rank eighth in the league in total defense and are allowing 20.8 points per game. On Sunday, Minnesota was unable to overcome a second quarter pick-six during a 28-22 home loss versus Philadelphia.

Minnesota QB Carson Wentz was under siege all afternoon from a fierce Philadelphia pass rush and finished with 313 passing yards. Jordan Mason carried 15 times for 57 yards and a score. Will Reichard booted five field goals, including a 59-yard bomb to get the Vikings on the scoreboard.

Chargers Preview

The Los Angeles Chargers are undefeated through three AFC West Division games and are a game behind Denver for first place. The Chargers (4-3) rank fourth in the league in total offense and are scoring 21.6 points per contest. Last week, Los Angeles was outscored by 17 points during the second quarter of a 38-24 home loss versus Indianapolis.

All-Pro QB Justin Herbert tried his best to rally Los Angeles with a season-high 420 passing yards and three touchdowns. Rookie TE Orande Gadsden II caught seven passes for 164 yards and a score. The Chargers committed a pair of turnovers and allowed 5.2 yards per rush to the Colts.

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Vikings vs Chargers Pick

Minnesota QB J.J. McCarthy (ankle) was inactive as the team’s emergency quarterback on Sunday. Los Angeles played last week without injured LT Joe Alt (ankle) and rookie RB Omarion Hampton (ankle). The Chargers are too banged up on the offensive line to be favored in this spot. Take the Vikings to win on the road. Final Score Prediction, Minnesota Vikings with 24-20.