Minnesota Vikings vs New York Giants Picks, Prediction, Odds, and Line Movement for Sunday December 21 2025

By: Devin Erickson-Sheehy Published 12/18/2025, 09:34 AM ET

Vikings vs Giants picks are front and center for this NFC matchup, and I am breaking down the betting angles as part of my NFL picks with Minnesota heading to The Meadowlands to take on New York.

TLDR: Quick Picks and Prediction

  • Spread: Vikings -2.5
  • Total: Over 43.5
  • Projected Final Score: Vikings 27, Giants 17

Odds and Line Movement

Current Odds

Team Spread Total
Vikings -2.5 (-122) Over 43.5 (-115)
Giants +2.5 (+100) Under 43.5 (-105)

Line Movement - Spread

Date Minnesota New York
12/15 -2.5 (-122) +2.5 (+100)
12/15 -2.5 (-118) +2.5 (-104)
12/15 -2.5 (-115) +2.5 (-105)
12/14 -1.5 (-110) +1.5 (-110)

Line Movement - Total

Date Over Under
12/15 43.5 (-115) 43.5 (-105)
12/15 44 (-105) 44 (-115)
12/14 42 (-105) 42 (-115)
12/09 41 (-115) 41 (-105)

Key Matchups and Game Preview

Minnesota earned a 28-6 road win at MetLife Stadium last season, holding a Daniel Jones-led Giants offense to just 240 total yards. This matchup once again tilts heavily toward the Vikings, who enter with significant momentum on both sides of the ball.

J.J. McCarthy has quickly re-established himself as one of the most intriguing young quarterbacks in the league. Over the last two weeks, Minnesota has out-scored Washington and Dallas by a combined margin of 65-26, with McCarthy completing 66.0 percent of his passes while throwing six touchdowns against just one interception.

With the benefit of hindsight, the Vikings difficult midseason stretch now makes more sense. From Weeks 7 through 13, Minnesota faced seven consecutive opponents that are all likely playoff teams, a brutal run against competition with a combined .660 winning percentage. Many young quarterbacks would struggle in that scenario.

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Now facing a three-game stretch against lesser competition, the Vikings offense looks far more comfortable and explosive. This is a number I am comfortable laying on the road.

New York has lost eight straight games and the Giants defense has allowed an average of 31.5 points per game during that stretch. Special teams issues continue to plague the Giants as well, with missed field goals and a punt return touchdown allowed in last week’s loss to Washington.

  • Minnesota has covered in back-to-back games.
  • New York has lost eight straight games.
  • The Giants are allowing 31.5 points per game during their losing streak.

Key Injuries and Things To Know (MIN and NYG)

  • Minnesota enters this game with growing confidence in its young quarterback.
  • New York continues to struggle on special teams.

Side and Over and Under Picks

  • Spread: Vikings -2.5
  • Total: Over 43.5

Final Score Prediction

Vikings 27, Giants 17

How to Wager On Vikings vs Giants

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