Philadelphia Eagles Vs Kansas City Chiefs Picks and Prediction for Sunday, September 14, 2025

By: Ricky Mackenzie Published 09/10/2025, 12:14 AM ET

Eagles vs Chiefs Preview

The Philadelphia Eagles enter this rematch of Super Bowl LIX off a narrow 24–21 win over the Dallas Cowboys. Get our free NFL Picks all season long! Their defensive front proved disruptive, and a late field goal sealed the victory. Now they travel to Arrowhead Stadium, armed with momentum and looking to take command early.

The Kansas City Chiefs are reeling from a surprising Week 1 loss in Brazil, falling 27–21 to the Chargers. Quarterback Patrick Mahomes looked limited by absences in the receiving corps and a struggling offensive rhythm. To bounce back, they’ll need creative scheming and quick adjustments.

Eagles Preview

For the Eagles, maintaining tempo and leveraging their defense will be essential. Jalen Hurts and the offense must protect the football and convert on third downs to avoid being pinned deep. Their ability to control time of possession could neutralize the Chiefs’ home-field advantage.

Chiefs Preview

The Chiefs must protect their quarterback better and reignite misfiring receivers. Sustaining drives and avoiding negative plays early can build confidence. If Mahomes can connect with key weapons, the offense could ascend late. Expect a better effort from the Chiefs on Sunday.

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Eagles vs Chiefs Pick

Kansas City must respond sharply and restore offensive flow, but the Eagles carry structure, rhythm, and edge in confidence. Expect a physical, chess-match game that swings on execution. Take the Eagles to win the game and to cover the spread with ease. Final Score Prediction, Philadelphia Eagles win 28-17.