Ottawa Senators vs Buffalo Sabres Stars Picks and Predictions for Wednesday, October 15, 2025

By: Cameron Ross Published 10/15/2025, 12:05 AM ET

Ottawa Senators vs Buffalo Sabres Information

The Ottawa Senators will be on the road Wednesday night for a game inside the KeyBank Center at 7:00 PM against the Buffalo Sabres. Ottawa has one win and two losses on the year, riding a 2-game skid into this matchup. The Buffalo Sabres will be back at home on Wednesday, coming into this game winless after three games this season. Stay in the news with our NHL Picks.

Ottawa Senators Preview

Offensively, Ottawa has been mediocre this season, with 2.67 goals on 31 shots per game. Defensively, Ottawa has been terrible, allowing 4.67 goals on 26 shots per game, with an average of five goals per game during their two losses this season. Shane Pinto leads the Ottawa offense this season with five points and four goals through three games played. Artem Zub and Jake Sanderson are both tied for second on the roster with three points each. Brady Tkachuk has also added three points this season, including the team-leading three assists.

Buffalo Sabres Preview

The Buffalo Sabres are the worst offensive team in the league this season, averaging .67 goals on 29.3 shots per game overall. Defensively, Buffalo has been just as bad, allowing 3.33 goals on just under 34 shots per game this season. Jason Zucker is one of five players on the roster to have scored at least one point this season for Buffalo. Tage Thompson has also added one point and one goal through three games played.

Ottawa Senators vs Buffalo Sabres Prediction

Despite the recent struggles, Ottawa is the better team in this matchup. Ottawa will overwhelm Buffalo from start to finish at night. Buffalo can't score the puck and will continue to struggle against Ottawa in this game. Take the Senators on Wednesday night to secure the win on the road against a terrible Buffalo team.  Final Score Prediction, Ottawa Senators win 3-1.

Sign Up Get $30 Premium Picks Credit + Exclusive Offers

Subscribe Now

I understand that I can unsubscribe at any time. I have read and accepted the Terms & Conditions and Privacy Policy. I consent that Picks And Parlays may use third-party services to process my data.

Never Tried Picks and Parlays? Now Is Your Chance

  • Get your first daily picks package for ONLY $1 using coupon code BUCK
  • If the pick loses, we credit your account with 3 Flex Picks
  • If the pick wins, we still give you 1 Flex Pick on the house
  • Win or lose, you walk away ahead. One dollar. No catch.
Onyx Odds

Spend $10 Get 200 in Bonus Picks

Show Bonus Code
Claim Bonus
Signup Promo Recommended Onyx Odds Bonus
Can be redeemed Yes
betr

$200 in No Sweat Entries + A Free Pick

Show Bonus Code
Claim Bonus
Signup Promo Hot Offer
Min. Purchase $10
Requirement $200 Betr Bucks maximum per user ($100 from each Qualifying Entry token)
Playthrough 1x Bonus
Can be redeemed Yes
Thrillzz

Get 100% on any coins purchase up to $100

Show Bonus Code
Claim Bonus
Signup Promo Hot Offer Thrillzz Bonus
Can be redeemed Yes
Video: Today's MLB BEST Bets: Brewers vs Padres + Royals vs Dodgers Picks and Predictions
Today's MLB BEST Bets: Brewers vs Padres + Royals vs Dodgers Picks and Predictions
Video: Daily Profit: Can The Seahawks REPEAT?? NFC West Betting Preview
Daily Profit: Can The Seahawks REPEAT?? NFC West Betting Preview

Senators vs Sabres Best Picks

  • Ottawa Senators -120
  • Under 6.5
logo

If you or someone you know has a gambling problem, crisis counseling and referral services can be accessed by calling 1-800-GAMBLER (1-800-426-2537) (IL). Gambling problem? Call 1-800-GAMBLER (MI/NJ/PA/WV/WY), 1-800-9-WITH-IT (IN), 1-800-522-4700 (CO), 1-800-BETS OFF (IA), 1-888-532-3500 (VA), 1-800-NEXT STEP (AZ), or call/text TN REDLINE 1-800-889-9789 (TN). 21+ (18+ WY). AZ/CO/IL/IN/IA/MI/NJ/PA/TN/VA/WV/WY only. Eligibility restrictions apply. T&C's Apply. Void where prohibited. If you click on a link on this site which takes you to a bookmaker or casino and you subsequently open an account, Pick and Parlays may receive a commission. Bets placed are the responsibility of the bettor.

Copyright © 2026 Picks and Parlays. All rights reserved.

The sports news and information contained at this site is for entertainment purposes only. Any use of this information in violation of laws whether they are federal, state and/or local is prohibited. Picks and Parlays is the nation's premier resource for sports betting and handicapping information.

Sign Up Get $30 Premium Picks Credit + Exclusive Offers
Special Offer
Spend $10 Get 200 in Bonus Picks
Play now T&Cs apply, 18+